Until now, researchers have assumed that the growth of solid tumors originates from cancer stem cells characterized by specific surface markers, which develop in a fixed, hierarchical order. Accordingly, such cancer stem cells are responsible for tumor progression and produce specific types of more differentiated cancer cells whose fates are predetermined. In a joint interdisciplinary project led by the Luxembourg Institute of Health (LIH), researchers now show that cancer cells of glioblastomas—conspicuously aggressive solid brain tumors—manifest developmental plasticity and their phenotypic characteristics are less constrained than believed. Cancer stem cells, including their progeny, are able to adapt to environmental conditions and undergo reversible transformations into various cell types, thereby altering their surface structures. The results imply that novel therapeutic approaches, which target specific surface structures of cancer
From https://medicalxpress.com/news/2019-05-cancer-cells-quick-change-artists-environment.html
From https://jamesjohnson10.blogspot.com/2019/05/cancer-cells-are-quick-change-artists.html
from
https://jamesjohnson10.wordpress.com/2019/05/28/cancer-cells-are-quick-change-artists-adapting-to-their-environment/
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