Senescent cells are a mechanism of aging, but also a mechanism of regeneration. When entering a senescent state, a cell shuts down replication and begins to secrete a mix of inflammatory and other signals, rousing the immune system and altering the behavior of surrounding cells. In addition to the other ways in which cells become senescent, in response to the Hayflick limit on cellular replication, or to potentially cancerous DNA damage, senescent cells also arise in response to injury. Their secretions help to guide the complicated dance of immune cells, stem cells, and somatic cells that takes place during the consequent regeneration. Afterwards, the senescent cells self-destruct via apoptosis, or are destroyed by the immune system. Unfortunately, it is never the case that all senescent cells
From https://jamesjohnson10.blogspot.com/2019/07/p53-hsp90-and-cellular-senescence-in.html
from
https://jamesjohnson10.wordpress.com/2019/07/25/p53-hsp90%ce%b2-and-cellular-senescence-in-muscle-regeneration-and-muscle-aging/
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