The progression of Alzheimer’s disease is very complicated, and yet to be fully understood, for all that there is a good catalog of the individual pathological mechanisms involved as the condition progresses: aggregation of amyloid-β and tau; persistent viral infection; chronic inflammation; dysfunction in the immune cells of the brain; and more. The question is how these mechanisms fit together into chains of cause and effect, a process of discovery that is complicated by the fact that order of progression or importance of specific mechanisms may be quite different between individuals, and some mechanisms have two-way relationships, in which either is capable of aggravating the other. Is Alzheimer’s disease a condition in which various factors cause amyloid-β deposition over the years, which causes glial
From https://jamesjohnson10.blogspot.com/2019/10/towards-more-glial-centric-view-of.html
from
https://jamesjohnson10.wordpress.com/2019/10/02/towards-a-more-glial-centric-view-of-alzheimers-disease/
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